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Clinical Infectious Diseases @cidjournal.bsky.social · about 2 hours ago
Ertapenem in Hypoalbuminemia: Methodological and Pharmacokinetic Considerations ✅ Just Accepted 🔗 bit.ly/4zQVjNh
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Ophthopedia @ophthalmology.bsky.social · 1 day ago
Ophthopedia Update: Endophthalmitis after cataract surgery in Sweden 2018-2024: associations with preoperative visual acuity and intracameral antibiotic regimens: WHAT IS ALREADY KNOWN ON THIS TOPIC * Postoperative endophthalmitis (PE) after cataract surgery… #Ophthalmology #Ophthotwitter #BJO
Endophthalmitis after cataract surgery in Sweden 2018-2024: associations with preoperative visual acuity and intracameral antibiotic regimens

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Endophthalmitis after cataract surgery in Sweden 2018-2024: associations with preoperative visual acuity and intracameral antibiotic regimens

WHAT IS ALREADY KNOWN ON THIS TOPIC * Postoperative endophthalmitis (PE) after cataract surgery is rare, and intracameral (IC) cefuroxime or moxifloxacin is widely used for prophylaxis, but comparative evidence between regimens remains limited. The association between preoperative visual acuity (VA) and the risk of PE has not been well established.WHAT THIS STUDY ADDS * In nearly one million Swedish cataract procedures, PE occurred in 0.013%; male sex, ocular comorbidity and capsule complication were associated with higher odds, whereas preoperative VA≥20/40 and immediate sequential bilateral cataract surgery were associated with lower odds. No IC antibiotic regimen was independently associated with a lower incidence, although microbial findings and clinical outcomes differed between regimens.HOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE OR POLICY * Preoperative VA and case mix should be considered when comparing endophthalmitis rates between populations, while larger studies with improved control of confounding are needed to determine the optimal IC antibiotic regimen.

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Liverpool School of Tropical Medicine @lstmnews.bsky.social · 1 day ago
Children with tuberculosis (TB) face a greater risk of serious illness and death than adults, but our new Start4Kids study is working to improve diagnosis and treatment. Funded by @Unitaid, we have recruited our first participant in Cameroon, enrolment is officially open. lstm.ac/Start4Kids
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KNCV TB Plus | KNCV Tuberculosis Foundation @kncvtbplus.bsky.social · 1 day ago
New research and our colleague Christiaan Mulder mentions that these findings highlight a critical opportunity: #TB programs need to look beyond treatment initiation and strengthen person-centred support throughout the entire TPT journey. 🔗Read the article here: academic.oup.com/ofid/art….
High Initiation but Suboptimal Completion of Tuberculosis-Preventive Treatment Among People Living With HIV on Antiretroviral Therapy, Persistent Tuberculosis Incidence, and Programmatic Implications:...

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High Initiation but Suboptimal Completion of Tuberculosis-Preventive Treatment Among People Living With HIV on Antiretroviral Therapy, Persistent Tuberculosis Incidence, and Programmatic Implications:...

Study showed that 3HP is well tolerated with high completion rates. Although programmatic tuberculosis-preventive treatment (TPT) completion was overestima

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