Kate Michie synbioaustralasia.org
SBA 2025 conference
SBA 2025 conference Synthetic Biology Australasia New Zealand synbio conference
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At #COP16Colombia, Parties adopted decision 16/21 on synthetic biology.
📽️ @unbiodiversity.bsky.social unpacks the significance of this decision and its relevance to the implementation of the Convention and the Kunming-Montreal Global Biodiversity Framework #KMGBF.
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The recent article by Walunjkar et al. on the evolution of protein thermostability is the focus of this month's Highlight feature.
Highlight: Cellular Environment and Protein Structure Help Organisms Cope with Temperature Stress
🔗 doi.org/10.1093/molbev/ms…
#evobio #molbio
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@shawnburks.bsky.social
about 1 hour agoIt's still comparable to auto-complete. Just because the language is DNA proteins doesn't change the underlying mechanic of how the model derives it's output.
I'm not anti-llm I think that it's a cool technology that can be useful but way too many people think that it's more than it is.
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AI models for drug discovery have a lot more knowledge about their domain structurally encoded into the models. These are highly specialized models that excel at difficult problems like predicting 3D protein structure based on amino acid sequences.
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Activating and inhibiting nucleotide signals coordinate bacterial anti-phage defense pubmed.ncbi.nlm.nih.gov/4… #cryoEM
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Excited to be speaking at Synthetic Biology Australasia 2025 in Wellington, New Zealand, 19–21 November!
I'll be sharing my group's recent advances on plant synthetic biology and genome engineering 🌱🧬
Join us:
🔗 synbioaustralasia.org/upc…
#SBA2025 #SyntheticBiology #ScienceInAction
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Choreography of human mitochondrial leaderless mRNA translation initiation pubmed.ncbi.nlm.nih.gov/4… #cryoEM
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Structural variability of apolipoprotein A-I amyloid fibrils across organs, mutations, and clinical presentations, revealed by cryo-EM pubmed.ncbi.nlm.nih.gov/4… #cryoEM
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Huge degradation in PPI prediction accuracy, but not monomeric prediction accuracy, when replacing MSAs with PLMs in a distilled version of the AF3 clone Protenix. This is attributed to lack of MSA pairing arxiv.org/pdf/2507.11839
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Congrats to #BioMBIB faculty scientist James Fraser! He received the Carl Brändén Award during the #PS39 @proteinsociety.bsky.social meeting for outstanding contributions to #ProteinScience that span research, education & service.
@fraserlab.com @berkeleylab.lbl.gov @ucsfmedicine.bsky.social
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Exploring the Intrinsic Structural Plasticity and Conformational Dynamics of Human Beta Coronavirus Spike Glycoproteins pubmed.ncbi.nlm.nih.gov/4… #cryoEM
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Meet the RCSB PDB at ACA 75 #aca2025
Join us for posters, presentations, and more at the 75th annual meeting of the American Crystallographic Association
Details: pdb101.rcsb.org/news...
pdb101.rcsb.org
PDB101: Meet the RCSB PDB at ACA 75
PDB-101: Training, Outreach, and Education portal of RCSB PDB
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Excited to share our Department of Neurobiology and Biophysics' new visual identity! Three panels capturing the essence of our work:
🔬 Cellular level
🧬 Molecular level
📊 Systems level
All inspired by the stunning PNW - trees, mountains, and water reflecting where science meets nature.
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Structural basis of lipopolysaccharide translocon assembly mediated by the small lipoprotein LptM pubmed.ncbi.nlm.nih.gov/4… #cryoEM
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@arxivlens.bsky.social
about 8 hours agoCryo-EM structures of naturally occurring dimeric photosystem II complexes lacking the Mn4CaO5 cluster
Maghlaoui, K., Nixon, P. J. et al.
Paper
Details
#CryoEMPhotosystemII #DimericComplexes #Mn4CaO5ClusterFree
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Structures of Chaetomium thermophilum TOM complexes with bound preproteins pubmed.ncbi.nlm.nih.gov/4… #cryoEM
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🧪 Ever wondered what the difference is between #cryoEM and #negativestain #TEM is? Find out in today's FAQ Friday!
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It has been a while (read - way too long!) since the last FSC weekend. Props to @guillawme.bsky.social for trying to revive this wonderful tradition, and perfectly timed for the weekend! #cryoEM 👀
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@healthdivine.bsky.social
about 9 hours ago🧬 Molecule magic! #MolecularModelling accelerates drug discovery & protein engineering 💻🔬
#ComputationalBiology #PharmaTech #DrugDev
www.marketresearchfuture.….
www.marketresearchfuture.com
Molecular Modelling Market Share, Trends | Growth Analysis By 2032
Molecular Modelling Market expected to reach 9.1% CAGR growth forecast period 2023-2032, Molecular Modelling Market Categorizes by Product, Application and Region |Molecular Modelling Industry
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A most excellent molecule with which to conclude the week #SynChem #BB #MedChem #cheminformatics #DrugDesign #DrugDiscovery
enaminestore.com/catalog/….
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gregory-ms.com/articles/2…
Perturbation response scanning of drug-target networks: Drug repurposing for multiple sclerosis
#MSchat #MS #Neurology #MultipleSclerosis #NeuroSky #NeuroSkyence
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