What is Psoriasis Club?
Find out here: psoriasisclub.com/about.html
#Psoriasis
psoriasisclub.com
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Psoriasis
by Flaky Fred @flakyfred.com This feed should pick up the word psoriasis and the #Psoriasis hashtag This feed only shows the last 7 days, to see more use the hashtag in a search.
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Live from Bluesky 
At Psoriasis Club you'll find a friendly bunch of people sharing information & support. We know what it's like living with psoriasis & have built up a huge amount of information on the topic.
We have no sponsors or advertising, we are just people living with #Psoriasis
psoriasisclub.org
psoriasisclub.org
Psoriasis Club
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Could targeting macrophage cannabinoid 1 receptor (CB1R) be a new therapeutic strategy for psoriasis ?
#Psoriasis
psoriasisclub.org/thread-….
psoriasisclub.org
Targeting cannabinoid 1 receptor and psoriasis
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Here you can see the clear line from an infection (COVID) to new onset autoimmune disease (Celiac).
This is a well-known pattern that plays out with many autoimmune diseases.
For me, it was strep throat ➡️ psoriasis.
Once you have one autoimmune disease, your risk of getting another increases.
MaskTogetherAmerica @togetherwemask.bsky.social
"Long COVID has been devastating and life-altering. It led to my diagnosis of Celiac diseass —as COVID-19 can disrupt the gut microbiome." —Erin Kay, Founder of Claiming Disability shares why she strongly advocates for masking. www.instagram.com/p/DefAbKmJcg... #MaskTogetherAmerica
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helps with fibromyalgia, anxiety,depression,ptsd,addiction, arthritis,insomnia, eczema,chronic pain, psoriasis, acne, sciatica, stress & much more. All cbd products are the highest quality & Lab Tested.
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Psoriatic Disease UK is run entirely by volunteers — people who live with or care deeply about these conditions, giving their time to support this community.
If what we do has ever helped you, thank you for being here.
#PsoriaticDisease #Psoriasis #Volunteers #ChronicIllness
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Discover personalized skin & hair care at Sharma Cosmo Clinic, Noida.
✔️ Psoriasis & Pimple Treatment
✔️ PRP & Plasma Therapy
✔️ Dandruff & Anti-Aging Care
📍 Sector 11, Noida
📞 +91 9810622372
🌐 sharmacosmoclinic.com
#SkinCare #HairCare #Noida
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Macrophages lacking INSIG1 worsen psoriasis via SREBP2-STAT1, with human lesions showing INSIG1 inversely linked to IL-23, IL-17A. Deeper insights into skin autoimmunity. PMID:42393041, Nat Commun 2026, @NatureComms doi.org/10.1038/s41467-02… #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
doi.org
Macrophage INSIG1 deficiency drives psoriasiform dermatitis via the SREBP2-STAT1 axis | Nature Communications
Psoriasis is an autoimmune skin disease, and its pathogenesis remains incompletely understood. As central drivers of psoriasis pathogenesis that bridge innate and adaptive immunity, macrophages are known to be modulated in their function by insulin-induced gene 1 (INSIG1), a regulator of cholesterol synthesis. Bioinformatic analysis of human psoriatic lesions reveals a significant negative correlation between INSIG1 expression and pro-inflammatory cytokine levels (IL-23, IL-17A). Single-cell RNA sequencing (scRNA-seq) and immunofluorescence confirm significantly reduced INSIG1 expression specifically in macrophages from psoriatic skin. In vivo, myeloid-specific Insig1 deficiency exacerbates imiquimod (IMQ)-induced psoriasiform dermatitis, characterized by increased epidermal thickening and immune infiltration. By activating sterol regulatory element-binding protein 2 (SREBP2), INSIG1 deficiency leads to the transcriptional upregulation of STAT1, which drives M1 macrophage polarization
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Finally made a phone call I've put off for a week that took less than 2 minutes. 🙃 I gotta remember my psoriasis clinic I've started going to is actually nice, fast, and efficient. They're still new with not that many patients, so we'll see how long that lasts, though. 👀
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Exercise is an important part of health
and can improve symptoms of #psoriasis
www.healio.com/news/dermato...
www.healio.com
High physical activity associated with lower psoriasis severity
A high level of physical activity was associated with less severe psoriasis, according to a study published in the Journal of the American Academy of Dermatology. These findings were consistent…
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