Feed for science posts related to genetics, genomics, DNA, RNA, heritability, genes, transcriptional regulation, bioinformatics, and computational biology. Tag posts with 🧬 to be included.
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Prevalence and Evolutionary Implications of Genome Rearrangements in Bacteria
Abstract. The genetic material of bacteria and archaea is organized into various structures and set-ups, attesting that genome architecture is dynamic in t
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doi.org
www.nature.com
Systematic review of preferences for additional findings from genomic testing - European Journal of Human Genetics
European Journal of Human Genetics - Systematic review of preferences for additional findings from genomic testing
doi.org
NEMO: Improved and accurate models for identification of 6mA using Nanopore sequencing
DNA methylation plays a key role in epigenetic regulation across lifeforms. Nanopore sequencing enables direct detection of base modifications. While multiple tools are currently available for studying 5-methylcytosine (5mC), there is a paucity of models that can detect 6-methyladenine (6mA) from raw nanopore data. Leveraging the motif-driven nature of bacterial methylation systems, we generated 6mA identification models that vastly surpass the accuracy of the current best model. Our work enables the study of 6mA at a single-base resolution in new as well as existing nanopore datasets. ### Competing Interest Statement DTS has received free consumables and travel support from Oxford Nanopore Technologies. Other authors declare no competing interests. Rockefeller Foundation, 2021 HTH 018 Department of Biotechnology, BT/PR40264/BTIS/137/44/2022
www.marketresearchfuture.com
South Korea Human Genetics Market Size, Growth Outlook 2035
South Korea Human Genetics Market growth is projected to reach 2155.6 USD billion, at a 11.739% CAGR by driving size, share, top company analysis, segments research, trends and forecast report 2025 to...
www.nature.com
phys.org
Chemists determine structure of fuzzy coat that surrounds Tau proteins
One of the hallmarks of Alzheimer's disease is the clumping of proteins called Tau, which form tangled fibrils in the brain. The more severe the clumping, the more advanced the disease is.
Alex Rubinsteyn 